Blister Management
EB blisters should be drained if they are tense or if they are 1/2 inch in diameter or larger. This is because the fluid inside the blister puts pressure on the surrounding skin, causing the layers of skin to split further, resulting in a larger blister and sore. A larger blister takes longer to heal and is at greater risk of becoming infected. It is also more painful than a smaller one. The side of the blister roof should be punctured or slit using a sterile needle, lancet or manicure scissors. If using a needle, be sure the opening in the blister is large enough that it will not seal and refill. Every effort should be made to leave the blister roof in place, as this improves comfort and healing.