Although it is not possible to completely prevent all blisters in people with EB, blistering can often be minimized through the use of special clothing, socks, and shoes. In addition, some children with EB blister less with the use of protective bandaging; that is, applying bandages and wraps to areas of the skin that are currently free of blisters. Areas such as the knees and elbows are often prone to blistering from trauma. Keeping these areas bandaged may minimize the effects of trauma on blistering.
In addition, sometimes adhesive bandages or tapes are applied to the skin, either accidentally or when there is no alternative to secure other medical devices. The use of special adhesive removers or the application of petrolatum ointments may be required to remove these adhesives with minimal damage to the skin.
Prevention of skin infection is an important part of EB skin care. Ways to minimize infection include careful attention to infection-control precautions during dressing changes, frequent use of hand sanitizers, and routine disinfection of wound care supplies and the bandaging area.